Powerful immunomagnetic negative or positive cell selection
products for:
negative or positive selection of HUMAN cells
negative selection of MOUSE cells
negative selection of RAT cells
negative selection of NON-HUMAN PRIMATE cells
negative selection of OTHER SPECIES cells
StemSep™ equipment
StemSep™ support reagents
What is StemSep™?
StemSep™ is a high performance system in which cells are immunomagnetically labeled and bound to a magnetic column. Cells which are specifically targeted for selection (depletion)are crosslinked to StemSep™ magnetic nanoparticles via STEMCELL’s patented TAC (tetrameric antibody complex) technology (Figures 1, 2). The labeled cell suspension is then passed through a high-gradient magnetic column of stainless steel mesh. The magnetically labeled cells bind to the column while the unlabeled cells pass through. Cells isolated by negative selection pass through the column untouched (Figure 3), while cells isolated by positive selection are collected from the column (Figure 4).
Is a StemSep™ magnet required?
If you currently use a column-based magnetic cell separation system, all you may need are the economical StemSep reagents of your choice. StemSep uses extremely tiny magnetic nanoparticles, which are retained in a positive or negative column placed in a 0.5 Tesla magnet. If you are not sure whether you can use your current magnetic system, please contact us at techsupport@stemcell.com.
StemSep™ negative selection advantages
StemSep™ positive selection advantages
Figure 1. Schematic drawing of StemSep™ magnetic labeling of a human, rat, or non-human primate cell
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Figure 2. Schematic drawing of StemSep™ magnetic labeling of a mouse cell
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Figure 3.
StemSep™ negative selection procedure | Figure 4.
StemSep™ positive selection procedure | .jpg) | .jpg) |
PLUS! Contact us to schedule a CELL SEPARATION product demonstration!
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